What setting on a burette pump is required to administer 100 mL of fluid containing 1 g flucloxacillin in 30 minutes?

What setting on a burette pump is required to administer 100 mL of fluid containing 1 g flucloxacillin in 30 minutes?

• A. 180 mL/h
• B. 190 mL/h
• C. 210 mL/h
• D. 200 mL/h

Answer: (D)

The key idea is that the infusion rate is volume divided by time. To deliver 100 mL in 30 minutes, first convert 30 minutes to hours (0.5 hours). Then the needed rate is 100 mL / 0.5 h = 200 mL per hour. Setting the burette pump to 200 mL/h will deliver exactly 100 mL over 30 minutes. If you use a slower rate, it would take longer than 30 minutes to deliver 100 mL; if you use a faster rate, it would finish in less than 30 minutes. The total amount of flucloxacillin (1 g) is fixed in the 100 mL and doesn’t change the required flow rate—the concentration determines how much drug is in each milliliter, not the time to deliver the volume.

The key idea is that the infusion rate is volume divided by time. To deliver 100 mL in 30 minutes, first convert 30 minutes to hours (0.5 hours). Then the needed rate is 100 mL / 0.5 h = 200 mL per hour. Setting the burette pump to 200 mL/h will deliver exactly 100 mL over 30 minutes. If you use a slower rate, it would take longer than 30 minutes to deliver 100 mL; if you use a faster rate, it would finish in less than 30 minutes. The total amount of flucloxacillin (1 g) is fixed in the 100 mL and doesn’t change the required flow rate—the concentration determines how much drug is in each milliliter, not the time to deliver the volume.